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Influenza - Flu

Vaccination with bovine, chick, yeast antigens synthesizes cross-reactive antibodies targeting human acetylcholine receptor and MuSK protein to cause Myasthenia Gravis: Confirmed by natural experiment (VAERS data), bioinformatics, case reports, animal experiments and titer study
Published: 2019
SYNOPSIS

Animal protein containing vaccines cause autoimmune diseases even when
the vaccine does not contain an adjuvant. Adjuvanted vaccines only make the problem worse.
Vaccines interact to cause autoimmune diseases.

CITATION

Arumugham, Vinu. Zenodo, 2019, September 16 http://doi.org/10.5281/zenodo.3421559.

SUMMARY

Myasthenia Gravis (MG) is a neuromuscular junction disorder, development of which is often reported following the administration of many vaccines. Most cases occur following administration of the influenza vaccines (per the Vaccine Adverse Event Reporting System-VAERS), most of which are manufactured using embryonated chicken eggs and contain residual egg proteins (AchR proteins). The chick proteins are very similar to the AchR proteins in human beings, so when the antibody production is directed against the chick protein there is a cross reaction with the human AchR, causing MG.

A similar mechanism is involved in Graves’ disease (GD). Yeast (Saccharomyces cerevisiae) is used to produce recombinant Hepatitis B vaccine (HBV), Human Papillomavirus vaccine (HPV) and injectable insulin products. We show significant protein sequence homology between GD autoepitopes, animal proteins and S. cerevisiae proteins. Humoral immune response directed against S. cerevisiae occurs following HBV, HPV administration and prolonged injectable insulin usage as in type 1 diabetes. Thus leading to the development of GD and numerous other autoimmune disorders.

The findings described add to the evidence that non-target antigens (NTA) in vaccines cause numerous disorders.

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Bilateral deafness two days following influenza vaccination: a case report
Published: 2019
SYNOPSIS

This case report describes bilateral deafness following influenza vaccination.

Citation

Kolarov C, Lobermann M, Fritsche C, Hemmer C, Mlynski R, Reisinger EC. Bilateral deafness two days following influenza vaccination: a case report. Human Vaccines & Immunotherapeutics. 2019;15(1):107-108.

 

Summary

This case report describes bilateral deafness following influenza vaccination in a 79-year-old woman with previously normal hearing.

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Bilateral deafness two days following influenza vaccination: a case report
Published: 2019
SYNOPSIS

This case report describes bilateral deafness following influenza vaccination.

CITATION

Kolarov C, Lobermann M, Fritsche C, Hemmer C, Mlynski R, Reisinger EC.  Human Vaccines & Immunotherapeutics. 2019;15(1):107-108.

SUMMARY

This case report describes bilateral deafness following influenza vaccination in a 79-year-old woman with previously normal hearing.

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Temporal Association of Certain Neuropsychiatric Disorders Following Vaccination of Children and Adolescents: A Pilot Case-Control Study
Published: 2017
SYNOPSIS

Yale scientists find strong association between vaccinations and anorexia, ocd, and anxiety disorder.

CITATION

Douglas L. Leslie, Robert A. Kobre, Brian J. Richmand. Frontiers in Psychiatry, January 2017.

SUMMARY

“Subjects with newly diagnosed anorexia nervosa were more likely than controls to have had any vaccination in the previous 3 months [hazard ratio (HR) 1.80, 95% confidence interval 1.21-2.68]. Influenza vaccinations during the prior 3, 6, and 12 months were also associated with incident diagnoses of AN, OCD, and an anxiety disorder. Several other associations were also significant with HRs greater than 1.40 (hepatitis A with OCD and AN; hepatitis B with AN; and meningitis with AN and chronic tic disorder). This pilot epidemiologic analysis implies that the onset of some neuropsychiatric disorders may be temporally related to prior vaccinations in a subset of individuals.”

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Autoimmune/inflammatory syndrome induced by adjuvants (ASIA) 2013: Unveiling the pathogenic, clinical and diagnostic aspects
Published: 2013
SYNOPSIS

Israeli and Italian researchers demonstrate that exposure to aluminum in vaccines can lead to autoimmune and brain dysfunction.

CITATION

Perricone C, Colafrancesco S, Mazor RD, Soriano A, Agmon-Levin N, Shoenfeld Y. Journal of Autoimmunity. 2013;47:1-16.

SUMMARY

Environmental factors play a critical role in the induction of autoimmunity, with an interplay between genetic susceptibility and environment. Several neurologic demyelinating diseases have been reported following vaccination, notably Guillain-Barre syndrome (GBS) and acute disseminated encephalomyelitis (ADEM) (an inflammatory disease of the central nervous system). A number of the most common vaccines appear to have some involvement with autoimmunity.

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Interindividual variations in the efficacy and toxicity of vaccines
Published: 2010
SYNOPSIS

Researchers warn of sizable difference in individual reaction to vaccines, stress need to avoid increasing side effects of vaccines.

CITATION

Chandan Thomasa, Majid Moridanib. Toxicology 278, 2010 204-210.

SUMMARY

“A number of currently available vaccines have shown significant differences in the magnitude of immune responses and toxicity in individuals undergoing vaccination. A number of factors may be involved in the variations in immune responses, which include age, gender, race, amount and quality of the antigen, the dose administered and to some extent the route of administration, and genetics of immune system. Hence, it becomes imperative that researchers have tools such as genomics and proteomics at their disposal to predict which set of population is more likely to be non-responsive or develop toxicity to vaccines.. With the increasing number of side effects associated with a number of vaccines reported over the years, it has become imperative to develop new technologies that can effectively assist in the development and evaluation of vaccines for efficacy and toxicity.”

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Post-vaccination encephalomyelitis: Literature review and illustrative case
Published: 2008
SYNOPSIS

Australian scientists describe the role of vaccines in triggering acute disseminated encephalomyelitis (“ADEM”).

CITATION

William Huynh, Dennis J. Cordato, Elias Kehdi, Lynette T. Masters, Chris Dedousis. Journal of Clinical Neuroscience, 15 (2008) 1315–1322.

SUMMARY

“Post-infectious and post-immunization encephalomyelitis make up about three-quarters of cases, where the timing of a febrile event is associated with the onset of neurological disease. Post-vaccination Acute disseminated encephalomyelitis has been associated with several vaccines such as rabies, diphtheria-tetanus-polio, smallpox, measles, mumps, rubella, Japanese B encephalitis, pertussis, influenza, hepatitis B, and the Hog vaccine. We review ADEM with particular emphasis on vaccination as the precipitating factor.”

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Repeated influenza vaccination of healthy children and adults: borrow now, pay later?
Published: 2006
SYNOPSIS

Repeated influenza vaccination at a young age substantially increases the risk of influenza at older ages.

CITATION

Carrat F, Lavenu A, Cauchemez S, Deleger S. Repeated influenza vaccination of healthy children and adults: borrow now, pay later? Epidemiology & Infection 2006;134(1):63-70.

SUMMARY

This study shows that repeated influenza vaccination at younger ages may double the risk of influenza in the elderly. The study suggests that the “possible benefits of vaccinating children after 5 years of age, and otherwise healthy adults—particularly over a long period and mainly for economic reasons—could be outweighed by severe clinical consequences and increased costs in the elderly.” Moreover, the findings are “solely due to differences between vaccine-induced immunity and naturally acquired immunity.” Unlike vaccination, naturally acquired immunity can provide long-lasting protection against subsequent infection by the same viral subtype.

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