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Hepatitis B – Hep B

Vaccination with bovine, chick, yeast antigens synthesizes cross-reactive antibodies targeting human acetylcholine receptor and MuSK protein to cause Myasthenia Gravis: Confirmed by natural experiment (VAERS data), bioinformatics, case reports, animal experiments and titer study
Published: 2019
SYNOPSIS

Animal protein containing vaccines cause autoimmune diseases even when
the vaccine does not contain an adjuvant. Adjuvanted vaccines only make the problem worse.
Vaccines interact to cause autoimmune diseases.

CITATION

Arumugham, Vinu. Zenodo, 2019, September 16 http://doi.org/10.5281/zenodo.3421559.

SUMMARY

Myasthenia Gravis (MG) is a neuromuscular junction disorder, development of which is often reported following the administration of many vaccines. Most cases occur following administration of the influenza vaccines (per the Vaccine Adverse Event Reporting System-VAERS), most of which are manufactured using embryonated chicken eggs and contain residual egg proteins (AchR proteins). The chick proteins are very similar to the AchR proteins in human beings, so when the antibody production is directed against the chick protein there is a cross reaction with the human AchR, causing MG.

A similar mechanism is involved in Graves’ disease (GD). Yeast (Saccharomyces cerevisiae) is used to produce recombinant Hepatitis B vaccine (HBV), Human Papillomavirus vaccine (HPV) and injectable insulin products. We show significant protein sequence homology between GD autoepitopes, animal proteins and S. cerevisiae proteins. Humoral immune response directed against S. cerevisiae occurs following HBV, HPV administration and prolonged injectable insulin usage as in type 1 diabetes. Thus leading to the development of GD and numerous other autoimmune disorders.

The findings described add to the evidence that non-target antigens (NTA) in vaccines cause numerous disorders.

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Bioinformatics and epidemiological evidence link yeast protein containing HPV and Hepatitis B vaccines to numerous autoimmune disorders such as vitiligo, narcolepsy, hypothyroidism, systemic lupus erythematosus and rheumatoid arthritis
Published: 2018
SYNOPSIS

Yeast proteins in the human papillomavirus (HPV) and hepatitis B vaccines—in combination with powerful adjuvants—can give rise to autoimmune reactions, and “non-target” proteins in other vaccines can do the same.

CITATION

Arumugham V. Bioinformatics and epidemiological evidence link yeast protein containing HPV and Hepatitis B vaccines to numerous autoimmune disorders such as vitiligo, narcolepsy, hypothyroidism, systemic lupus erythematosus and rheumatoid arthritis. Zenodo 2018. http://doi.org/10.5281/zenodo.1435404.

SUMMARY

This bioinformatics analysis confirms that recombinant vaccines containing yeast and immune-boosting adjuvants—the human papillomavirus (HPV) and hepatitis B vaccines—can produce “off-target” autoimmune responses due to molecular mimicry between yeast proteins and human self-proteins. In fact, this failure mechanism affects all vaccines due to vaccines’ use of non-target food, animal, viral, bacterial or fungal proteins as growth media and excipients. Narcolepsy (a sleep disorder) and vitiligo (a skin disorder) are just two of the many autoimmune conditions associated with the HPV and hepatitis B vaccines.

 

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Interindividual variations in the efficacy and toxicity of vaccines
Published: 2010
SYNOPSIS

Researchers warn of sizable difference in individual reaction to vaccines, stress need to avoid increasing side effects of vaccines.

CITATION

Chandan Thomasa, Majid Moridanib. Toxicology 278, 2010 204-210.

SUMMARY

“A number of currently available vaccines have shown significant differences in the magnitude of immune responses and toxicity in individuals undergoing vaccination. A number of factors may be involved in the variations in immune responses, which include age, gender, race, amount and quality of the antigen, the dose administered and to some extent the route of administration, and genetics of immune system. Hence, it becomes imperative that researchers have tools such as genomics and proteomics at their disposal to predict which set of population is more likely to be non-responsive or develop toxicity to vaccines.. With the increasing number of side effects associated with a number of vaccines reported over the years, it has become imperative to develop new technologies that can effectively assist in the development and evaluation of vaccines for efficacy and toxicity.”

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Hepatitis B vaccination of male neonates and autism diagnosis, NHIS 1997-2002
Published: 2010
SYNOPSIS

SUNY-Stony Brook scientists find boys receiving the hepatitis B vaccine series are three times more likely to have autism.

CITATION

Gallagher C, Goodman M. Journal of Toxicology and Environmental Health, Part A. 2010;73:1665–1677.

SUMMARY

“Boys vaccinated as neonates had threefold greater odds for autism diagnosis compared to boys never vaccinated or vaccinated after the first month of life. Findings suggest that U.S. male neonates vaccinated with the hepatitis B vaccine prior to 1999 (from vaccination record) had a threefold higher risk for parental report of autism diagnosis compared to boys not vaccinated as neonates during that same time period.”

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Delayed acquisition of neonatal reflexes in newborn primates receiving a thimerosal-containing Hepatitis B vaccine: Influence of gestational age and birth weight
Published: 2009
SYNOPSIS

Newborn monkeys given a mercury-containing hepatitis b vaccine had significant delays in neonatal reflexes and neurological development.

CITATION

Laura Hewitson, Lisa A. Houser, Carol Stott, Gene Sackett, Jaime L. Tomko, David Atwood, Lisa Blue, E. Railey White, Andrew J. Wakefield. NeuroToxicology, 2009; doi:10.1016/j.neuro.2009.09.008.

SUMMARY

“In summary, this study provides preliminary evidence of abnormal early neurodevelopmental responses in male infant rhesus macaques receiving a single dose of Th-containing HB vaccine at birth and indicates that further investigation is merited.”

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Hepatitis B triple series vaccine and developmental disability in US children aged 1-9 years
Published: 2008
SYNOPSIS

Boys receiving the hepatitis B vaccine series were nine times more likely to need special education and be developmentally disabled.

CITATION

Gallagher C, Goodman M. Toxicological and Environmental Chemistry. 2008;90(5):997-1008.

SUMMARY

This study investigated the association between vaccination with the hepatitis B triple series vaccine (pre-2000) and subsequent developmental disability. The odds of receiving special education were approximately nine times as great for vaccinated boys as for unvaccinated boys, after adjustment for confounders. The evidence, statistically significant, suggests that boys in United States who were vaccinated with the triple series hepatitis B vaccine were more susceptible to developmental disability than were unvaccinated boys.

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Post-vaccination encephalomyelitis: Literature review and illustrative case
Published: 2008
SYNOPSIS

Australian scientists describe the role of vaccines in triggering acute disseminated encephalomyelitis (“ADEM”).

CITATION

William Huynh, Dennis J. Cordato, Elias Kehdi, Lynette T. Masters, Chris Dedousis. Journal of Clinical Neuroscience, 15 (2008) 1315–1322.

SUMMARY

“Post-infectious and post-immunization encephalomyelitis make up about three-quarters of cases, where the timing of a febrile event is associated with the onset of neurological disease. Post-vaccination Acute disseminated encephalomyelitis has been associated with several vaccines such as rabies, diphtheria-tetanus-polio, smallpox, measles, mumps, rubella, Japanese B encephalitis, pertussis, influenza, hepatitis B, and the Hog vaccine. We review ADEM with particular emphasis on vaccination as the precipitating factor.”

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Iatrogenic exposure to mercury after hepatitis B vaccination in preterm infants
Published: 2000
SYNOPSIS

Vaccines with mercury significantly raised the body levels of mercury in infants.

CITATION

Gregory V. Stajich, Gaylord P. Lopez, Sokei W. Harry, and William R. Sexson. Journal of Pediatrics, 2000, 136, 679-81.

SUMMARY

“Thimerosal, a derivative of mercury, is used as a preservative in hepatitis B vaccines. We measured total mercury levels before and after the administration of this vaccine in 15 preterm and 5 term infants. Comparison of pre- and post-vaccination mercury levels showed a significant increase in both preterm and term infants after vaccination. Additionally, post-vaccination mercury levels were significantly higher in preterm infants as compared with term infants. Because mercury is known to be a potential neurotoxin to infants, further study of its pharmacodynamics is warranted.”

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