Some individuals are at risk of developing autoimmune/inflammatory syndrome induced by adjuvants (ASIA).
Predicting post-vaccination autoimmunity: who might be at risk?
Soriano A, Nesher G, Shoenfeld Y. Pharmacological Research, 2015;92:18-22. Epub 2014 Sep 30.
It has been postulated that autoimmunity could be triggered or enhanced by a vaccine’s immunogen contents, as well as by adjuvants, which are used to increase the immune reaction to the immunogen. Fortunately, vaccination-related ASIA (autoimmune/inflammatory syndrome induced by adjuvants) is uncommon. Yet, by defining individuals at risk, it may be possible to further limit the number of individuals developing post-vaccination ASIA.