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Immunization

Association Between Aluminum Exposure From Vaccines Before Age 24 Months and Persistent Asthma at Age 24 to 59 Months
Published: 2022
SYNOPSIS

To assess the association between cumulative aluminum exposure from vaccines before age 24 months and persistent asthma at age 24 to 59 months.

CITATION

M. F. Daley, M.D.; L. M. Reifler, MPH; J. M. Glanz, Ph.D.; S. J. Hambidge, M.D., Ph.D.; D. G., M.D., Ph.D.; S. A. Irving, MHS; J. D. Nordin, M.D., MPH; D. L. McClure, Ph.D.; N. P. Klein, M.D., Ph.D.; M. L. Jackson, Ph.D., MPH; S. Kamidani, M.D.; J.Duffy, M.D., MPH; Frank DeStefano, M.D.

SUMMARY

In a large observational study, a positive association was found between vaccine-related aluminum exposure and persistent asthma. While recognizing the small effect sizes identified and the potential for residual confounding, additional investigation of this hypothesis appears warranted.

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