In utero exposure to mercury and childhood overweight or obesity: counteracting effect of maternal folate status
In this US urban, multi-ethnic population, elevated in utero Hg exposure was associated with a higher risk of over weight / obesity in childhood, and such risk was enhanced by maternal over weight / obesity and/or diabetes and reduced by adequate maternal folate.
Low-dose mercury (Hg) exposure has been associated with cardiovascular diseases, diabetes, and obesity in adults, but it is unknown the metabolic consequence of in utero Mercury exposure. This study aimed to investigate the association between in utero Mercury exposure and child overweight or obesity (OWO) and to explore if adequate maternal folate can mitigate Mercury toxicity.
A number of factors can predispose susceptible individuals to autoimmune reactions following vaccination.
Vadalà M, Poddighe D, Laurino C, Palmieri B. European Association for Predictive Preventive & Personalized Medicine Journal. 2017;8(3):295-311.
This review discusses possible underlying mechanisms of autoimmune reactions following vaccinations and cases of autoimmune diseases that have been correlated with vaccination. Molecular mimicry and bystander activation are possible mechanisms by which vaccines can cause autoimmune reactions. The individuals who might be susceptible to develop these reactions could be those with previous post-vaccination phenomena, those with allergies, individuals who are prone to develop autoimmune diseases (such as those with a family history of autoimmunity or with known autoantibodies) and genetically predisposed individuals.