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Science Library Abstract
Published: 2019
SYNOPSIS

Out-of-sequence vaccinations may increase child mortality.

TITLE

Out-of-sequence DTP and measles vaccinations and child mortality in Guinea-Bissau: a reanalysis.

CITATION

Thysen SM, Rodrigues A, Aaby P, et al.  British Medical Journal Open 2019;9:e024893; doi:10.1136/bmjopen-2018-024893.

SUMMARY

This study’s objective was to assess whether the sequence of diphtheria-tetanus-pertussis vaccine (DTP) and measles vaccine (MV) was associated with child survival. Using a data set previously used to assess non-specific effects of vaccines with no consideration of vaccination sequence researchers found that out-of-sequence vaccinations in children were associated with higher mortality compared with children vaccinated in-sequence.

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