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Silicone

Autoimmune/inflammatory syndrome induced by adjuvants (Shoenfeld’s syndrome): clinical and immunological spectrum
Published: 2013
SYNOPSIS

Scientists from Mexico and Israel explain adjuvants (aluminum) used in vaccines can induce autoimmunity.

CITATION

Vera-Lastra O, Medina G, Del-Pilar Cruz Dominguez M, Jara LJ. Expert Reviews-Clinical Immunology. 2013;9(4):361-373.

SUMMARY

Activation of the immune system by adjuvants could trigger manifestations of autoimmunity or autoimmune disease. Autoimmune/inflammatory syndrome induced by adjuvants (ASIA) includes postvaccination phenomena, macrophagic myofasciitis (MMF), Gulf War syndrome and siliconosis. Various adjuvants used in vaccines enhance a specific immune response against antigens and may produce autoimmunity and autoimmune disease in experimental models and humans. “The clinical and laboratory data support an association between adjuvants and autoimmune diseases.”

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