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Science Library Abstract
Published: 2005
SYNOPSIS

Among girls, those who received both BCG and DTP experienced higher mortality than those who received only one of the two vaccines (hazards ratio 2.4; 95% confidence interval 1.2-5.0).

TITLE

Evaluation of non-specific effects of infant immunization on early infant mortality in southern Indian population.

CITATION

Moulton LH, Rahmathullah L, Halsey NA, Thulasiraj RD, Katz J, Tielsch JM. Tropical Medicine and International Health, 2005 Oct;10(10):947-55.

SUMMARY

In a study of children under 2 years of age in Guinea-Bissau, Kristensen et al. (2000) found immunization with Bacille Calmette Guerin (BCG) vaccine to be associated with lower mortality, but stated that oral polio vaccine (OPV) and diphtheria, tetanus, polio (DTP) vaccines were associated with higher mortality. More recently, it has been suggested that this effect may be gender-specific, existing primarily among girls. This evaluation, focused on relating timing of BCG and DTP vaccine receipt to mortality from 1 week to 6 months of age, with emphasis on gender differentials found that girls that received both BCG and DTP experienced higher mortality than those who received only one of the two vaccines.

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