Science Library Abstract
Published: 2002
SYNOPSIS

Utah state scientists find autoimmune reaction to MMR in children with autism, including autoimmunity to myelin basic protein, a brain building-block.

TITLE

Abnormal Measles-Mumps-Rubella Antibodies and CNS Autoimmunity in Children with Autism

CITATION

Vijendra K. Singh, Sheren X. Lin, Elizabeth Newell, Courtney Nelson. Journal of Biomedical Science, 2002, 9:359–364.

SUMMARY

“And, as described herein, autistic children showed a serological correlation between MMR and brain autoimmunity, i.e., over 90% of MMR antibody-positive autistic sera also had autoantibodies to brain MBP. This is quite an intriguing observation in favor of a connection between atypical measles infection and autism; an atypical infection usually refers to infection that occurs in the absence of a rash. An atypical measles infection in the absence of a rash and unusual neurological symptoms was recently described to suggest the existence of a variant MV in children and adults [9]. In light of these new findings, we suggest that a considerable proportion of autistic cases may result from an atypical measles infection that does not produce a rash but causes neurological symptoms in some children. The source of this virus could be a variant MV or it could be the MMR vaccine.”

TAGS