SYNOPSIS
Genetic and environmental factors can interact to trigger vaccine adverse events, but researchers’ understanding of genetic susceptibility is still limited.
TITLE
The ontology of genetic susceptibility factors (OGSF) and its application in modeling genetic susceptibility to vaccine adverse events
CITATION
Lin Y, He Y. The ontology of genetic susceptibility factors (OGSF) and its application in modeling genetic susceptibility to vaccine adverse events. J Biomed Semantics 2014;5:19.
SUMMARY
Vaccination can trigger adverse events in population subgroups with genetic susceptibility, often in interaction with environmental factors. These authors argue for the need for a “consensus-based robust…framework for systematically representing and studying…genetic susceptibility and the genetic factors contributing to the susceptibility.”
