SYNOPSIS
This preliminary study provides evidence that post-vaccination abnormal autoimmunity plays an important role in the development of unique symptoms after HPV vaccination.
TITLE
Autoantibodies against Autonomic Nerve Receptors in Adolescent Japanese Girls after Immunization with Human Papillomavirus Vaccine
CITATION
SUMMARY
In Japan a significant number of adolescent girls complain of unusual symptoms after human papillomavirus (HPV) vaccination that are considered adverse effects of HPV vaccination. However, a causal link between HPV vaccination and these adverse effects has not been demonstrated. In the present study, we investigated autoantibodies against diverse G-protein coupled receptors in the serum of girls who complained of possible adverse effects after HPV vaccination. This preliminary study provides evidence that post-vaccination abnormal autoimmunity plays an important role in the development of unique symptoms after HPV vaccination.