Science Library Category:

Hepatitis B

Published: 2018
SYNOPSIS

Indian study reveals birth dose of Hepatitis B vaccine is unnecessary.

TITLE

Evaluation of the Protection Provided by Hepatitis B Vaccination in India

CITATION

Puliyel, J., Naik, P., Puliyel, A. et al. Indian Journal of Pediatrics, (2018). https://doi.org/10.1007/s12098-017-2601-0.

SUMMARY

In India, Hepatitis B vaccination is recommended at 6 wk except for hospital-deliveries. The authors examined protection afforded by the birth dose and found that birth vaccination has no added protection when compared to the unvaccinated. Children who were fully vaccinated with or without birth dose of the hepatitis B vaccine had similar levels of protection against the infection.

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Published: 2018
SYNOPSIS

The neonatal hepatitis B vaccination induced an anti-inflammatory response lasting for 4–5 weeks.

TITLE

IL-4 mediates the delayed neurobehavioral impairments induced by neonatal hepatitis B vaccination that involves the down-regulation of the IL-4 receptor in the hippocampus

CITATION

Xiao Wang Junhua Yang, Zhiwei Xing, Hongyang Zhang, Yaru Wen, Fangfang Qi, Zejie Zuo, Jie Xu, Zhibin Yao. Cytokine, Volume 110, October 2018, Pages 137-149.

SUMMARY

These experiments showed that IL-4 mediates the delayed neurobehavioral impairments induced by neonatal hepatitis B vaccination, which involves the permeability of neonatal blood–brain barrier and the down-regulation of IL-4 receptor. This finding suggests that clinical events concerning neonatal IL-4 over-exposure, including neonatal hepatitis B vaccination and allergic asthma in human infants, may have adverse implications for brain development and cognition.

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Published: 2018
SYNOPSIS

Thimerosal contributes to the formation of abnormal proteins associated with Alzheimer’s and other diseases.

TITLE

Thimerosal changes protein conformation and increase the rate of fibrillation in physiological conditions: Spectroscopic studies using bovine serum albumin (BSA)

CITATION

Santos JCN, da Silva IM, Braga TC, de Fátima Å, Figueiredo IM, Santos JCC. Thimerosal changes protein conformation and increase the rate of fibrillation in physiological conditions: Spectroscopic studies using bovine serum albumin (BSA). International Journal of Biological Macromolecules. 2018;113:1032-1040.

SUMMARY

A series of experiments suggests that the effects of the vaccine preservative thimerosal on the structure of important protein molecules in the blood are one likely cause of thimerosal’s toxicity, contributing to the development of neurodegenerative and other diseases. Using a cow protein as a proxy to assess thimerosal’s impact on human serum albumin (a protein made by the liver), the study found that thimerosal accelerates the build-up of abnormal protein deposits that are associated with at least 25 diseases, including Alzheimer’s, Parkinson’s and type 2 diabetes. When bound to albumin, thimerosal also may result in “more efficient distribution” of mercury in the body.

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Published: 2017
SYNOPSIS

Yale scientists find strong association between vaccinations and anorexia, ocd, and anxiety disorder.

TITLE

Temporal Association of Certain Neuropsychiatric Disorders Following Vaccination of Children and Adolescents: A Pilot Case-Control Study

CITATION

Douglas L. Leslie, Robert A. Kobre, Brian J. Richmand. Frontiers in Psychiatry, January 2017.

SUMMARY

“Subjects with newly diagnosed anorexia nervosa were more likely than controls to have had any vaccination in the previous 3 months [hazard ratio (HR) 1.80, 95% confidence interval 1.21-2.68]. Influenza vaccinations during the prior 3, 6, and 12 months were also associated with incident diagnoses of AN, OCD, and an anxiety disorder. Several other associations were also significant with HRs greater than 1.40 (hepatitis A with OCD and AN; hepatitis B with AN; and meningitis with AN and chronic tic disorder). This pilot epidemiologic analysis implies that the onset of some neuropsychiatric disorders may be temporally related to prior vaccinations in a subset of individuals.”

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Published: 2007
SYNOPSIS

Neonatal deaths following hepatitis B vaccination should be investigated as possible vaccine-related deaths.

TITLE

An investigation of infant deaths following initial hepatitis B vaccination based on the Vaccine Adverse Event Reporting System (VAERS), 1992-2002

CITATION

Soldatenkova VA, Yazbak FE. An investigation of infant deaths following initial hepatitis B vaccination based on the Vaccine Adverse Event Reporting System (VAERS), 1992-2002. Medical Veritas. 2007;4:1414-1421.

SUMMARY

This study argues that all unexpected neonatal deaths occurring after initial hepatitis B vaccination should be systematically investigated. Over one-fifth (22%) of neonatal hepatitis B vaccine injuries reported to the U.S. Vaccine Adverse Event Reporting System (VAERS) from 1992 to 2002 were deaths (38/170) that, in nearly all cases, occurred within hours or days of vaccination. Although most of the deaths were officially classified as sudden infant death syndrome (SIDS) or “unexplained” rather than as vaccine-related deaths, the authors note “a statistically significant increase in [the] proportion of neonatal SIDS since implementation of universal vaccination of newborns against hepatitis B.” The VAERS reports also are suggestive of higher risks for premature, small, or slightly ill infants.

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