Autoimmune/inflammatory Syndrome Induced by Adjuvants (ASIA; Shoenfeld’s syndrome) comprehends a group of autoimmune conditions that flourish in genetically predisposed individuals, following an external stimulus by the so-called adjuvants. Many adjuvants were described, such as vaccines, aluminum and other metals, silicone, tattoos, among others. Here we report on a case of an 18-year-old woman who presented with extreme cachexia due to severe dysautonomia caused by the ASIA syndrome induced by the tetanus, diphtheria, and pertussis vaccine (Tdap).
Dysautonomia following Tetanus, Diphtheria, and Pertussis vaccine (Tdap): The first case of extreme cachexia caused by autoimmune/inflammatory syndrome induced by adjuvants (ASIA syndrome) in a human 2022
Hen, Or et al. “Dysautonomia Following Tetanus, Diphtheria, and Pertussis Vaccine (Tdap): The First Case of Extreme Cachexia Caused by Autoimmune/Inflammatory Syndrome Induced by Adjuvants (ASIA Syndrome) in a Human.” Medicina (Kaunas, Lithuania) vol. 57,12 1333. 6 Dec. 2021, doi.org/10.3390/medicina57121333
This is a case study of an 18-year-old female who presents with severe cachexia (wasting disease). Post-vaccination she experienced headaches, dizziness, arthralgia, myalgia, extreme fatigue, orthostatic intolerance, mouth ulcers and new food and pollen allergies, that she still deals with. Cachexia has gotten progressively worse since vaccination. She was diagnosed with ASIA following the Tdap vaccination given when she was 14 years old. This is based in part on high titers of anti-tetanus antibodies present in her immune system.
Israeli and Italian researchers demonstrate that exposure to aluminum in vaccines can lead to autoimmune and brain dysfunction.
Autoimmune/inflammatory syndrome induced by adjuvants (ASIA) 2013: Unveiling the pathogenic, clinical and diagnostic aspects
Perricone C, Colafrancesco S, Mazor RD, Soriano A, Agmon-Levin N, Shoenfeld Y. Journal of Autoimmunity. 2013;47:1-16.
Environmental factors play a critical role in the induction of autoimmunity, with an interplay between genetic susceptibility and environment. Several neurologic demyelinating diseases have been reported following vaccination, notably Guillain-Barre syndrome (GBS) and acute disseminated encephalomyelitis (ADEM) (an inflammatory disease of the central nervous system). A number of the most common vaccines appear to have some involvement with autoimmunity.