ADD/ADHD
SYNOPSIS
Metabolism of metals and toxins may play a role in ADHD and autism development, evidence may be detectable.
TITLE
Dynamical properties of elemental metabolism distinguish attention deficit hyperactivity disorder from autism spectrum disorder
CITATION
Austin et al. Translational Psychiatry (2019) 9:238 https://doi.org/10.1038/s41398-019-0567-6
SUMMARY
Cyclical processes involved in the metabolism of essential and toxic elements during fetal and early postnatal development differ significantly in children with attention deficit-hyperactivity disorder (ADHD) and/or autism spectrum disorder (ASD) and neurotypical children, according to a small study of tooth matrix biomarkers. The study’s findings suggest that metabolic regulation of nutrients and toxins may play a role in the development of ADHD and autism.
TAGS
SYNOPSIS
The prevalence of diagnosed ADHD in U.S. children and adolescents significantly increased over two decades, from 6.1% (1997-1998) to 10.2% (2015-2016).
TITLE
Twenty-year trends in diagnosed attention-deficit/hyperactivity disorder among US children and adolescents, 1997-2016
Citation
Xu G, Strathearn L, Liu B, Yang B, Bao W. JAMA Network Open. 2018;1(4):e181471.
Summary
Among U.S. children and adolescents, the estimated prevalence of diagnosed ADHD increased significantly between 1997-1998 and 2015-2016, from 6.1% to 10.2%. The continuous increase in the prevalence of diagnosed ADHD was consistent across all subgroups.
TAGS
SYNOPSIS
Neurodevelopmental disorders are much more common in children who received mercury-containing vaccines.
TITLE
A dose-response relationship between organic mercury exposure from thimerosal-containing vaccines and neurodevelopmental disorders
CITATION
Geier DA, Hooker BS, Kern JK, King PG, Sykes LK, Geier MR. International Journal of Environmental Research and Public Health. 2014;11:9156-9170.
SUMMARY
On a per microgram of organic-mercury (Hg) basis, pervasive developmental disorder, specific developmental disorder, tic disorder and hyperkinetic syndrome of childhood cases were significantly more likely than controls to receive increased organic-Hg exposure. This study provides new epidemiological evidence supporting a significant relationship between increasing organic-Hg exposure from vaccines and the subsequent risk of a neurodevelopmental disorder diagnosis.
TAGS
SYNOPSIS
A CDC-sponsored database showed much higher rates of neurodevelopmental disabilities from mercury-containing vaccines.
TITLE
Thimerosal exposure in infants and neurodevelopmental disorders: An assessment of computerized medical records in the Vaccine Safety Datalink
CITATION
Young HA, Geier DA, Geier MR. Journal of the Neurological Sciences. 2008;121:626-631.
SUMMARY
“Consistent significantly increased rate ratios were observed for autism, autism spectrum disorders, tics, attention deficit disorder, and emotional disturbances with Hg [mercury] exposure from TCVs [thimerosal-containing vaccines]. By contrast, none of the control outcomes had significantly increased rate ratios with Hg exposure from TCVs.”
TAGS
SYNOPSIS
Scientists identify vaccine mercury’s role in blocking crucial neurodevelopmental pathways.
TITLE
Activation of methionine synthase by insulin-like growth factor-1 and dopamine: a target for neurodevelopmental toxins and thimerosal
CITATION
M Waly, H Olteanu, R Banerjee, S-W Choi, JB Mason, BS Parker, S Sukumar, S Shim,
A Sharma, JM Benzecry, V-A Power-Charnitsky and RC Deth. Molecular Psychiatry , (2004) 9, 358–370.
SUMMARY
“The ethylmercury-containing preservative thimerosal inhibited both IGF-1- and dopamine-stimulated methylation with an IC50 of 1nM and eliminated MS activity. Our findings outline a novel growth factor signaling pathway that regulates MS activity and thereby modulates methylation reactions, including DNA methylation. The potent inhibition of this pathway by ethanol, lead, mercury, aluminum and thimerosal suggest that it may be an important target of neurodevelopmental toxins.”